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Upcoming Vaccinology Course

UNIVERSITY OF NAIROBI

 KAVI-INSTITUTE OF CLINICAL RESEARCH

IS OFFERING A FIVE (5) DAY COURSE ON

VACCINES AND IMMUNIZATION

Venue/Country: KAVI-ICR, University of Nairobi, Kenya

Dates: 25TH-29TH SEPTEMBER 2017

Costs: $150 per -person

Introduction:

Although a lot has been achieved in diagnosis and treatment of many medical conditions, emerging and re-emerging infectious diseases remain a major threat to global health, causing severe morbidity and mortality worldwide. To mitigate against these emerging and re-emerging infectious diseases the World Health Organization (WHO) global plan for vaccines 2011 to 2020 endorsed by 194 countries, aims at strengthening current routine immunization by accelerating control of vaccine preventable diseases, introducing new and improved vaccines and spurring research and development of the next generation of vaccines and technologies. New knowledge and technology for research and development for vaccine and other biologicals is emerging. Individuals, communities, healthcare professionals, universities and governments have primary responsibility for exploiting these emerging technologies to confront the challenges that this decade brings and the forecast global challenges of the future. Understanding how vaccines are developed, how vaccines work and legal issues in vaccination are some of the topics that will be addressed in this course.

Broad objective: Strengthen the capacity within Sub Saharan Africa in the field of vaccines and immunization

Who should attend?

  • Clinicians
  • Pharmacists
  • Laboratory Scientists
  • Nurses
  • Public Health Professionals
  • Healthcare professionals interested in clinical aspects of vaccine delivery
  • Post-graduate students (public health and clinical fields)
  • Policy makers
  • Managers of vaccine programs
  • Bio-Ethics and Regulatory members

At the end of this course the participants should be able to know:

  • The concepts and principles of vaccines and immunization
  • How and why vaccines are made
  • Immunological mechanisms for vaccine protection.
  • New technology and  ideas contributing to future vaccines development and
  • delivery
  • Impact of vaccines and immunization in the control of infectious diseases.

Training Methods: Teaching will be in the form of lectures, case studies, debates and visits to clinical research facilities. KAVI-ICR will provide training materials to participants.

 

How to Register;

Fill the registration form online or Download the form attached, fill, scan and send to the email below before 09TH SEPTEMBER 2017; Email to: This email address is being protected from spambots. You need JavaScript enabled to view it.    

Other Details;

  1. Course payment instructions will be given soon after registration
  2. Subsistence allowance and accommodation to be arranged & paid for by the Participants.

 

 

 

Upcoming Vaccinology Course

UNIVERSITY OF NAIROBI

KAVI-INSTITUTE OF CLINICAL RESEARCH

IS OFFERING A FIVE (5) DAY COURSE ON

VACCINES AND IMMUNIZATION

Venue/Country: KAVI-ICR, University of Nairobi, Kenya

Dates: May 8th – May 12th 2017

Costs: $150 per -person

Introduction:

Although a lot has been achieved in diagnosis and treatment of many medical conditions, emerging and re-emerging infectious diseases remain a major threat to global health, causing severe morbidity and mortality worldwide. To mitigate against these emerging and re-emerging infectious diseases the World Health Organization (WHO) global plan for vaccines 2011 to 2020 endorsed by 194 countries, aims at strengthening current routine immunization by accelerating control of vaccine preventable diseases, introducing new and improved vaccines and spurring research and development of the next generation of vaccines and technologies. New knowledge and technology for research and development for vaccine and other biologicals is emerging. Individuals, communities, healthcare professionals, universities and governments have primary responsibility for exploiting these emerging technologies to confront the challenges that this decade brings and the forecast global challenges of the future. Understanding how vaccines are developed, how vaccines work and legal issues in vaccination are some of the topics that will be addressed in this course.

Broad objective: Strengthen the capacity within Sub Saharan Africa in the field of vaccines and immunization

Who should attend?

  • Clinicians
  • Pharmacists
  • Laboratory Scientists
  • Nurses
  • Public Health Professionals
  • Healthcare professionals interested in clinical aspects of vaccine delivery
  • Post-graduate students (public health and clinical fields)
  • Policy makers
  • Managers of vaccine programs
  • Bio-Ethics and Regulatory members

At the end of this course the participants should be able to know:

  • The concepts and principles of vaccines and immunization
  • How and why vaccines are made
  • Immunological mechanisms for vaccine protection.
  • New technology and  ideas contributing to future vaccines development and
  • delivery
  • Impact of vaccines and immunization in the control of infectious diseases.

Training Methods: Teaching will be in the form of lectures, case studies, debates and visits to clinical research facilities. KAVI-ICR will provide training materials to participants.

How to Register;

Fill the registration form online or Download the form attached, fill, scan and send to the email below on or before 21th April 2017;

Email to: This email address is being protected from spambots. You need JavaScript enabled to view it.    

Other Details;

  1. Course payment instructions will be given soon after registration
  2. Subsistence allowance and accommodation to be arranged & paid for by the Participants.

 Download form here.

 

World AIDS Day 2016

On Thursday 1st  December 2016, the entire world commemorated World AIDS Day. The day is important to commemorate the lives lost to HIV/AIDS, inform and educate the public on issues regarding HIV/AIDS, promote stigma reduction towards HIV/AIDS-infected and affected individuals and discuss risk-reduction strategies.

The Theme of the Day was “Hands Up for HIV prevention among adolescents and youth”, therefore activities of the day concentrated on these groups.

Adolescents and young people represent a growing share of people living with HIV worldwide. In 2015 alone, 670,000 young people between the ages of 15 and 24 were newly infected with HIV, of whom 250,000 (37%) were adolescents between the ages of 15 and 19. To compound this, most recent data indicate that only 13 per cent of adolescent girls and 9 per cent of adolescent boys aged 15-19 in sub-Saharan Africa – the region most affected by HIV – have been tested for HIV in the past 12 months and received the result of the last test. If current trends continue, hundreds of thousands more will become HIV-positive in the coming years. Additionally, AIDS-related deaths among adolescents have increased over the past decade while decreasing among all other age groups, which can be largely attributed to a generation of children infected with HIV perinatally that are growing into adolescence (UNICEF, 2015).

In 2015, a new global strategy was launched which aims to end the AIDS epidemic by 2030. To achieve this, it is critical to accelerate efforts to address the epidemic among adolescents and young people. Therefore, the ALL IN! to End Adolescent AIDS agenda was launched in early 2015 in partnership with international health and development partners. This agenda established 2020 targets to better position the global AIDS response to end the AIDS epidemic among adolescents by 2030.

Despite the presence of antiretroviral drugs in the market, HIV/AIDS has claimed 34 million people’s lives so far. Current data from the World Health Organization (WHO), states that in 2014, an estimated 37 million people worldwide were living with HIV, with about 2 million new infections (WHO, 2015).

Children are also greatly affected by the burden of this disease; about 2.6 million children were living with HIV in 2014. Close to 220,000 children became newly infected with HIV in 2014. Most of these children live in Sub-Saharan Africa. Sub-Saharan Africa accounts for approximately 70% of new HIV infections globally. In addition, about 25.8 million people were living with HIV in 2014.

These appalling statistics clearly demonstrate HIV/AIDS is still a persistent public health problem globally. Hence the significance of celebrating World AIDS Day annually to combat this lethal disease. World AIDS Day 2016 promoted themes of achieving the Sustainable Development Goal to end the epidemic by the year 2030 and reducing the stigma of the disease among adolescents and the youth. Current estimates presented at the event put the number of people receiving antiretroviral treatment globally at 16 million, while 21 million of those infected remain untreated.

In Kenya, several counties were hosting the World AIDS day event but the national event was marked at the Nyayo National in Nairobi County. There were several important dignitaries scheduled to attend the event and address the public. Some of the dignitaries included: the American ambassador to Kenya, Mr. Robert Godec; NACC director Nduku Kilonzo; as well as representatives from UNAIDS, UNICEF, UNFPA, Global Fund and WHO. KAVI-Institute of Clinical Research (KAVI-ICR) had an exhibition stand and the director, Prof. Omu Anzala, was represented by Dr. Borna Nyaoke at the V.I.P dais.

The chief guest was initially His Excellency the president of Kenya, Uhuru Kenyatta, but due to other commitments, the First Lady Mrs. Margaret Kenyatta presided over the event, serving as the chief guest speaker. Mrs. Kenyatta highlighted the importance of seeking HIV testing to become aware of one’s status in order to reduce the spread of HIV/AIDS. She mentioned that currently, girls between the ages of 15-24 years have the highest proportion of new HIV infections among adults, standing at 21% (NACC, 2015). She emphasized that should infection rates among the youth keep rising, it would pose a threat to the wellbeing of the future generations and affect the productivity of the nation.

The First Lady informed the public that Kenya is one of the 10 countries in Africa selected to participate in the DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored and Safe) Initiative project in conjunction with the USA via the Bill and Melinda Gates Foundation, Girl Effect and PEPFAR. The DREAMS project will utilize a multi-thronged approach towards the combat of HIV/AIDS and assist in achieving the goals of Zero HIV infections, Zero AIDS related deaths, Zero Stigma and Zero Discrimination. She concluded the speech by encouraging Kenyans to envision achieving the 2030 goal and a HIV/AIDS-free generation becoming a reality.

Aside from the speeches made, there were many organizations with stands to promote awareness of HIV/AIDS, drug/alcohol abuse, free medical check-ups, free HIV testing and counseling and a healthy lifestyle. These included: non-governmental organizations (NGOs) such as the AIDS Healthcare Foundation; Asian companies promoting herbal medicine for controlling HIV/AIDS symptoms; Kenyatta National Hospital; National AIDS Control Council (NACC); National Authority for the Campaign against Alcohol and Drug Abuse (NACADA); Red Cross- Kenya and  KAVI-ICR.  The coming together of these groups and more, speak to the sentiment that “turning the tide against HIV/AIDS will require a more multifaceted approach more on adolescents and young people”.

We proudly represented KAVI-ICR by informing the public about the organization, past and current research undertaken and encouraged interested parties to provide their contact details for recruitment in the studies. It was interesting to note that most people want an HIV vaccine to end or control the epidemic, and the people who were familiar with the organization were eager to know the progress of the vaccine research. The potential volunteers’ questions were addressed as appropriate. Most of the feedback we received from answering their queries and informing them about KAVI-ICR and its work were positive. Given our active participation in representing KAVI-ICR, increasing awareness of the organization and its work on the HIV/AIDS vaccine, we are hopeful it will assist in expanding its community base and establishing more networks with potential partners.

In conclusion, the overall experience participating at the World AIDS Day brought to light the importance of healthcare professionals and citizens striving to form partnerships in order to control the HIV/AIDS epidemic. These multiple partnerships engage all levels of stakeholders thus resulting in finding effective solutions towards the fight against the of HIV/AIDS scourge.

KAVI – Institute of Clinical Research Bioethics Training Workshop

“Compared to just a few years ago, there are many more research institutions, and therefore an increased need for bioethics support,” opened Professor Walter Jaoko, the Deputy Director of KAVI – ICR. Prof. Walter Jaoko, Dr. Gaudensia Mutua, Jacqueline Nyange, Bashir Farah and the institute’s Director Prof. Omu Anzala  were among the trainers from KAVI – ICR conducting the Bioethics Training Workshop held from 1st to 3rd of March 2017.

If there was one take-home message, it’s that there are no easy answers in bioethics; this was typified in the spirited debates regarding issues presented as case studies over the course of the training.

One such example: a volunteer in a product trial is injured, and cannot afford medical care. What is the duty of the researcher to the participant if the injuries are outside of the study? What is the role, if any, of the ethics committee which approved the study? The answer, of course, is that there is simply not one perspective or approach to be applied absolutely.

As the body mandated to “regulate and assure quality in the science, technology and innovation sector”, the National Commission for Science, Technology and Innovation (NACOSTI) requires any institutional review board (IRB) or ethical review committee (ERC) to undergo bioethics training; KAVI – ICR conducts these trainings in collaboration with NACOSTI.

Aside from the lively discussions, sessions included learning about unethical research practices in history, community involvement in research, studies concerning vulnerable groups, data safety monitoring, legal aspects of bioethics and the formation of standard operating procedures.

As the participants had been appointed by their institutions to sit in ethical review committees, the training also explored: the role of such committees, essential elements of a research proposal and the review process to be followed.

“The role of IRBs is to facilitate research and not to frustrate it,” Prof. Walter Jaoko emphasised to participants – mostly from African International University and United States International University, and with that pertinent message brought the three day workshop to a close.

 

By Joy Muthure – This email address is being protected from spambots. You need JavaScript enabled to view it.

MUCOSAL SAMPLING AND IMMUNOLOGY TRAINING

MUCOSAL SAMPLING AND IMMUNOLOGY TRAINING

18th-20th JANUARY 2016

KAVI-INSTITUTUE OF CLINICAL RESEARCH (ICR)

KAVI-ICR conducted a mucosal sampling and immunology training from the 18th-22nd January 2016 held at KAVI-ICR research laboratory. The participants were drawn from laboratory scientist from India. Transmission of HIV-1 occurs predominantly across the genital mucosa during sexual intercourse. Consequently there is a growing interest in understanding host mucosal responses to HIV-1 during infection, and in assessing protective mucosal responses during microbicide and HIV vaccine trials. It is thus necessary to obtain samples from mucosal surfaces for immunological analysis in a standardized and reproducible manner, ensuring comparable data across studies and research centers. KAVI-ICR developed a 5-day hands-on training program on the collection and processing of mucosal samples, and transferred the techniques to research staff from India.

 

 

 

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